Giulia Casorati
San Raffaele Scientific Institute in Milano, Italy
Giulia Casorati is Head of the Experimental Immunology Unit at San Raffaele Scientific Institute in Milano, Italy. She obtained a PhD in Human Genetics at the University of Torino, Italy working on the genetic structure of TCR and immunoglobulin variable regions. Between 1988-91, she joined Klaus Karjalainen lab at the Basel Institute for Immunology, where she studied the structure of the TCRs ab and gd and contributed to the identification of human invariant NKT cells together with Paolo Dellabona and Antonio Lanzavecchia. Her group has been investigating fundamental mechanisms and translational aspects of the T cell immune response in cancer, with particular emphasis on CD1-restricted T and NKT cells both in transgenic mouse models generated in the laboratory, or in physiologic and pathologic human contexts. More recently she designed new adoptive immunotherapy protocols with lipid specific TCRs engineered T and iNKT cells to target CD1c+ hematologic malignancies.